Skip to main content
. Author manuscript; available in PMC: 2023 Apr 28.
Published in final edited form as: ACS Chem Neurosci. 2022 Dec 15;14(1):119–135. doi: 10.1021/acschemneuro.2c00597

Figure 7. Effect of Ariadne in behavioral conflict paradigms.

Figure 7.

(a) Survival plot of effect of (R)-Ariadne (10 mg/kg) on latency to feed in the novelty suppressed feeding (NSF) test 7 days post a single drug administration. (b) Effect of 6 mg/kg and 10 mg/kg (R)-Ariadne on latency to feed in the novelty suppressed feeding (NSF) test 7 days post a single drug administration. (c) Effect of (R)-Ariadne and (rac)-DOPR on the time spent in the open vs closed arms and (d) corresponding arm entries 30 minutes and 4 hours post a single subcutaneous injection. Kaplan–Meier survival analysis, Mantel–Cox log-rank test (a) and two-way ANOVA (c, d) with post-hoc Dunnett’s test. All values represented as mean ± S.E.M, n = 10 /group, ****p < 0.0001