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. 2023 Apr 28;13:6935. doi: 10.1038/s41598-023-33655-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Model comparisons. (A) The prediction accuracy of models built using different dataset preparations for refined selected-AEs (n = 10–13); (B) the prediction accuracy of different tissue models. ‘All’ column indicates average of all four-tissue-type (n = 2016) and ‘intestine’ column indicates average of three intestinal segments except stomach (n = 1554), stomach and ileum (n = 462), duodenum and colon (n = 546); (C) the prediction accuracy of model trained using different classification algorithms (n = 336). Data represents the mean ± S.D. Significant differences are indicated as *p < 0.05, **p < 0.01, ***p < 0.001 using paired t-tests.