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. 2023 Mar 13;199(1):13–23. doi: 10.1007/s10549-023-06895-2

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Cell viability assay in breast cancer cell lines. MEN1611 showed an improved in vitro antiproliferative potential in p110β-driven cellular models (PTEN loss breast cancer cells) compared to alpelisib and taselisib, while the antiproliferative activity in PIK3CA H1047R and K111N mutated breast cancer cell lines was similar among all drugs