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WNT7A retains nuclear YAP/TAZ and decreases FAP adipogenesis
(A) During adipogenesis, YAP/TAZ translocate to cytosol. WNT7A promotes nuclear retention of YAP/TAZ within the nucleus, thereby preventing FAP adipogenesis.
(B) WNT7A may rescue mechanical unloading-induced FAP adipogenesis by reinforcing YAP/TAZ activity through cell contractility-mediated mechanisms.
