Figure S6. Transcriptomic analysis of xPHF8ΔC rescue in SUV4-20H morphant ACs.

(A, C) To investigate whether transcript levels of cilium and cytoskeleton genes, which were down in the initial SUV4-20H1/2 KD dataset, had improved, we compare the log₂fold change between H1H2Mo versus CoMo-injected animal caps with log₂ fold change of xPHF8ΔC rescue versus xPHF8ΔC alone injected animal caps for cilium (A) and cytoskeleton (C) genes. Dashed line indicates no difference in expression upon xPHF8ΔC rescue. Genes above the line have improved expression and genes below the line are further down-regulated. (B, D) Change in expression of cilium (B) and cytoskeleton genes (D) that were down-regulated by SUV4-20H1/2 KD upon xPHF8ΔC rescue.