Table 2. Associations Between Levine EEA and Various Outcomes.

Outcome and group	OR or HR (95% CI)a	P value
Early-onset obesity
Age <20 y	1.46 (1.19-1.78)	2.19 × 10−4
Severity burden of all CHCs
Overall	1.13 (1.03-1.24)	8.03 × 10−3
Aged <20 y	1.06 (0.88-1.28)	5.16 × 10−1
Aged ≥20 y	1.21 (1.08-1.35)	7.24 × 10−4
Late mortality
Overall	1.75 (1.35-2.26)	1.90 × 10−5

Abbreviations: CHCs, chronic health conditions; Levine EEA, epigenetic age acceleration using the Levine clock; OR, odds ratio; HR, hazard ratio.

^a Cox proportional hazards regression was used for late mortality, with HR reported; logistic regression was used for other outcomes, with OR reported.