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. 2023 Apr 28;6(4):e2310800. doi: 10.1001/jamanetworkopen.2023.10800

Table 4. Cox Regression Analysis Assessing 60-Day Mortality Factors Associated With Risk in Congenital Diaphragmatic Hernia.

Factor Black Hispanic White
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Disease severity
Cardiovascular anomalies 1.51 (0.62-3.69) .37 1.57 (0.81-3.05) .18 0.76 (0.56-1.04) .08
Days on nitric oxide 0.98 (0.97-0.99) .03 0.99 (0.97-1.01) .30 0.99 (0.98-1.00) .17
ECLS 4.66 (1.45-15.01) .01 14.82 (4.63-47.42) <.001 7.50 (4.77-11.81) <.001
Institutional
High volume hospitala 0.91 (0.46-1.83) .80 0.76 (0.41-1.39) .37 0.74 (0.29-1.86) .52
Racial and ethnic diversityb
<30% 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA
31%-40% 0.17 (0.04-0.78) .02 0.40 (0.14-1.12) .08 0.68 (0.30-1.58) .38
>40% 0.64 (0.29-1.41) .27 0.37 (0.15-0.89) .03 1.15 (0.51-2.63) .73

Abbreviations: ECLS, extracorporeal life support; NA, not applicable.

a

High volume hospitals indicates those with 10 or more cases per year.

b

Racial and ethnic diversity is the percentage of Black/Hispanic patients with congenital diaphragmatic hernia treated.