Table 1.

Comparison of eMERGE and PHOEBE concept set-based algorithms’ performance. PPV – positive predictive value, CUIMC – Columbia University Irving Medical Center EHR, MDCR - IBM MarketScan® Medicare Supplemental Database, MDCD - IBM MarketScan® Multi-State Medicaid Database.

		eMERGE cohort			PHOEBE cohort			Cohort overlap
		Patients with subsequent treatment	Total	PPV	Patients with subsequent treatment	Total	PPV
Diabetes mellitus type I	CUIMC	7,599	25,701	0.34	7,659	25,884	0.34	25,635
	MDCD	25,954	191,710	0.13	26,240	194,100	0.13	189,810
	MDCR	19,274	185,874	0.10	18,684	181,712	0.11	179,236
Diabetes mellitus type II	CUIMC	42,200	211,904	0.20	44,828	218,127	0.21	211,903
	MDCD	342,975	1,807,688	0.19	383,435	1,849,177	0.21	1,807,019
	MDCR	105,449	386,265	0.27	804,415	2,172,925	0.37	386,237
ADHD	CUIMC	5,922	29,890	0.20	7,002	35,291	0.20	29,890
	MDCD	722,485	1,471,559	0.49	809,093	1,657,347	0.49	1,471,542
	MDCR	7,158	17,065	0.42	7,875	18,535	0.43	17,065
Heart Failure	CUIMC	71,281	162,297	0.44	74,121	168,111	0.44	162,281
	MDCD	332,929	870,080	0.38	342,112	893,807	0.38	869,500
	MDCR	892,689	1,166,980	0.76	919,077	1,204,488	0.76	1,165,900