Fig. 7.

Dual-modality imaging of bio-targeted oxygen production probes in vivo. A FL imaging and metabolic distribution of bio-targeted oxygen production probes in vivo. B Quantitative FL intensity of tumor tissue at 24 h, 32 h, 48 h, 54 h. C Biodistribution of bio-targeted oxygen production probes in tumor and significant organs. D Quantitative FL signal of bio-targeted oxygen production probes in tumor and major organs. E PA imaging and F quantitative PA intensity of tumor after injection of bio-targeted oxygen production probes at 6 h, 24 h, 48 h, 54 h