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. 2023 Apr 25;16:2441–2451. doi: 10.2147/IDR.S392504

Table 3.

Results of Univariate Logistic Regression Showing Factors Associated with Pregnancy Outcome and NICU Admission

Variables Pregnancy Outcome NICU Admission
OR P value 95% CI OR P value 95% CI
Age 1.712 0.009 1.141–2.567 1.509 0.043 1.013–2.248
Number of pregnancy 1.202 0.142 0.940–1.537 1.260 0.066 0.958–1.613
Number of birth 1.071 0.684 0.770–1.491 1.168 0.364 0.836–1.632
Number of abortions 1.380 0.005 1.099–1.932 1.458 0.001 1.157–1.837
GA at exposure 2.675 <0.001 1.871–3.825 3.068 <0.001 2.123–4.434
Complication 0.967 0.287 0.910–1.028 0.994 0.855 0.935–1.058
Delivery type (normal—ref)
 Cesarean section 3.432 <0.001 2.154–5.471 3.547 <0.001 2.224–5.658
 Obstetric forceps 8.523 0.007 1.785–40.686 7.935 0.009 1.663–37.850
Drug delivery route
 Parenteral 1.411 0.327 0.709–2.811 1.669 0.144 0.839–3.320
 Oral 0.567 0.558 0.085–3.798 0.237 0.216 0.024–2.325
 Vaginal 0.519 0.195 0.193–1.398 0.499 0.173 0.183–1.357
 Combined 1.700 0.496 0.368–7.845 1.184 0.821 0.274–5.121
Single/combined use 1.745 0.009 1.150–2.649 1.827 0.005 1.201–2.779
Drug dose (DDD) 0.537 <0.001 0.420–0.685 0.623 <0.001 0.493–0.788
Narrow/Broad spectrum 1.049 0.767 0.9763–1.443 1.110 0.524 0.806–1.528
Antimicrobial classification (None-ref)
 First-generation cephalosporins 3.632 0.006 1.445–9.126 2.977 0.015 1.233–7.190
 Second-generation cephalosporins 0.638 0.343 0.251–1.617 0.711 0.471 0.281–1.800
 Third-generation cephalosporins 0.768 0.495 0.36–1.638 0.928 0.847 0.436–1.976
 Antimycotics 0.340 0.065 0.108–1.070 0.379 0.097 0.121–1.191
 Macrolides 1.558 0.464 0.476–5.104 1.737 0.361 0.531–5.683
 Nitroimidazoles 3.683 0.070 0.897–15.118 4.105 0.050 1.001–16.836
 Penicillins 0.567 0.361 0.168–1.917 0.829 0.760 0.249–2.757
 Combined 2.947 0.014 1.241–6.997 3.020 0.011 1.284–7.100

Notes: P<0.05; P<0.01; P<0.001.

Abbreviation: DDD, defined daily dose.