Table 3.
Results of Univariate Logistic Regression Showing Factors Associated with Pregnancy Outcome and NICU Admission
| Variables | Pregnancy Outcome | NICU Admission | ||||
|---|---|---|---|---|---|---|
| OR | P value | 95% CI | OR | P value | 95% CI | |
| Age | 1.712 | 0.009▲ | 1.141–2.567 | 1.509 | 0.043● | 1.013–2.248 |
| Number of pregnancy | 1.202 | 0.142 | 0.940–1.537 | 1.260 | 0.066 | 0.958–1.613 |
| Number of birth | 1.071 | 0.684 | 0.770–1.491 | 1.168 | 0.364 | 0.836–1.632 |
| Number of abortions | 1.380 | 0.005▲ | 1.099–1.932 | 1.458 | 0.001▲ | 1.157–1.837 |
| GA at exposure | 2.675 | <0.001★ | 1.871–3.825 | 3.068 | <0.001★ | 2.123–4.434 |
| Complication | 0.967 | 0.287 | 0.910–1.028 | 0.994 | 0.855 | 0.935–1.058 |
| Delivery type (normal—ref) | ||||||
| Cesarean section | 3.432 | <0.001★ | 2.154–5.471 | 3.547 | <0.001★ | 2.224–5.658 |
| Obstetric forceps | 8.523 | 0.007▲ | 1.785–40.686 | 7.935 | 0.009▲ | 1.663–37.850 |
| Drug delivery route | ||||||
| Parenteral | 1.411 | 0.327 | 0.709–2.811 | 1.669 | 0.144 | 0.839–3.320 |
| Oral | 0.567 | 0.558 | 0.085–3.798 | 0.237 | 0.216 | 0.024–2.325 |
| Vaginal | 0.519 | 0.195 | 0.193–1.398 | 0.499 | 0.173 | 0.183–1.357 |
| Combined | 1.700 | 0.496 | 0.368–7.845 | 1.184 | 0.821 | 0.274–5.121 |
| Single/combined use | 1.745 | 0.009▲ | 1.150–2.649 | 1.827 | 0.005▲ | 1.201–2.779 |
| Drug dose (DDD) | 0.537 | <0.001★ | 0.420–0.685 | 0.623 | <0.001★ | 0.493–0.788 |
| Narrow/Broad spectrum | 1.049 | 0.767 | 0.9763–1.443 | 1.110 | 0.524 | 0.806–1.528 |
| Antimicrobial classification (None-ref) | ||||||
| First-generation cephalosporins | 3.632 | 0.006▲ | 1.445–9.126 | 2.977 | 0.015● | 1.233–7.190 |
| Second-generation cephalosporins | 0.638 | 0.343 | 0.251–1.617 | 0.711 | 0.471 | 0.281–1.800 |
| Third-generation cephalosporins | 0.768 | 0.495 | 0.36–1.638 | 0.928 | 0.847 | 0.436–1.976 |
| Antimycotics | 0.340 | 0.065 | 0.108–1.070 | 0.379 | 0.097 | 0.121–1.191 |
| Macrolides | 1.558 | 0.464 | 0.476–5.104 | 1.737 | 0.361 | 0.531–5.683 |
| Nitroimidazoles | 3.683 | 0.070 | 0.897–15.118 | 4.105 | 0.050 | 1.001–16.836 |
| Penicillins | 0.567 | 0.361 | 0.168–1.917 | 0.829 | 0.760 | 0.249–2.757 |
| Combined | 2.947 | 0.014● | 1.241–6.997 | 3.020 | 0.011● | 1.284–7.100 |
Notes: ●P<0.05; ▲P<0.01; ★P<0.001.
Abbreviation: DDD, defined daily dose.