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. Author manuscript; available in PMC: 2023 Oct 26.
Published in final edited form as: Metabolomics. 2022 Oct 26;18(11):84. doi: 10.1007/s11306-022-01944-1

Table 1.

The pathways significantly altered between the mice on an isoflavone diet compared to the mice on a phyto-free diet. The pathway analysis parameters included the Global Test for the enrichment methods and the Relative-betweenness Centrality for the topology analysis.

Pathway p-value FDR

Purine metabolism 0.00023888 0.012539
Selenocompound metabolism 0.00041796 0.012539
Tryptophan metabolism 0.0012081 0.024162
Thiamine metabolism 0.0027655 0.040851
Aminoacyl-tRNA biosynthesis 0.0055593 0.040851
Galactose metabolism 0.0065999 0.040851
Arachidonic acid metabolism 0.0067309 0.040851
Linoleic acid metabolism 0.0067309 0.040851
alpha-Linolenic acid metabolism 0.0067309 0.040851
Starch and sucrose metabolism 0.0068085 0.040851
Phenylalanine metabolism 0.0082912 0.045225
Vitamin B6 metabolism 0.012389 0.061946