Table 2.
Comparison of acetonitrile (ACN) and methanol (MEOH) solvents in the extraction of QC analytes by a QuEChERS in food sample matrices.
| Compounds | Log Kow | Monitored ions (m/z) | Detection mode | ACN | MEOH | ACN/MEOH |
|---|---|---|---|---|---|---|
| Sucralose | −1 | 395.007 | − | 514975 | 138609 | 3.7 |
| Hydrochlorothiazide | −0.1 | 295.957 | − | 30492507 | 6973708 | 4.3 |
| Caffeine | 0.16 | 195.088 | + | 173896997 | 40041329 | 4.3 |
| Lincomycin | 0.29 | 407.221 | + | 69941827 | 226729204 | 0.30 |
| Sulfamethoxazole | 0.48 | 254.059 | + | 510609753 | 302274447 | 1.6 |
| Trimethoprim | 0.73 | 291.145 | + | 798986842 | 293952394 | 2.7 |
| Norcocaine | 1.96 | 290.139 | + | 2508331676 | 651262182 | 3.8 |
| Carbamazepine | 2.25 | 237.102 | + | 1220011570 | 746093554 | 1.6 |
| Diltiazem | 2.79 | 415.169 | + | 2009629433 | 150171042 | 13.3 |
| Atrazine | 2.82 | 216.101 | + | 4379749352 | 2080194051 | 2.1 |
| Diphenhydramine | 3.11 | 256.17 | + | 2955706292 | 1517110694 | 1.9 |
| Diclofenac | 4.02 | 294.009 | − | 122921945 | 34465135 | 3.5 |
| Fluoxetine | 4.65 | 310.141 | + | 3852011163 | 1149551446 | 3.3 |
| Gemfibrozil | 4.77 | 249.15 | − | 37854518 | 2360833 | 16.0 |
| Mefenamic acid | 5.28 | 240.103 | − | 105742980 | 32179184 | 3.2 |
| Sertraline | 5.29 | 306.081 | + | 732006025 | 98904061 | 7.4 |
| Clotrimazole | 6.26 | 345.115 | + | 266510368 | 82800462 | 3.2 |