Table 1.
Characteristics of CALERIE Trial participants at baseline
| AL | CR | |||
|---|---|---|---|---|
| N/mean | (%/s.d.) | N/mean | (%/s.d.) | |
| CALERIE participant characteristics at baseline | ||||
| Age at baseline (yr) | 38 | (7) | 38 | (7) |
| Energy intake (kcal d−1) | 2,045 | (481) | 2,124 | (558) |
| Sex | ||||
| Women | 53 | (71%) | 100 | (69%) |
| Men | 22 | (29%) | 45 | (31%) |
| Race/ethnic identity | ||||
| White | 57 | (76%) | 111 | (77%) |
| Black | 11 | (15%) | 16 | (11%) |
| Other | 7 | (9%) | 18 | (12%) |
| Study site | ||||
| A | 25 | (33%) | 47 | (32%) |
| B | 27 | (36%) | 53 | (37%) |
| C | 23 | (31%) | 45 | (31%) |
| BMI stratum | ||||
| 22.0–24.9 kg m−2 | 37 | (54%) | 70 | (48%) |
| 25.0–27.9 kg m−2 | 38 | (55%) | 75 | (52%) |
| Analysis sample characteristics at baseline | ||||
| Age at baseline | 38 | (7) | 38 | (7) |
| Energy intake (kcal d−1) | 2,023 | (469) | 2,130 | (540) |
| Sex | ||||
| Women | 48.00 | (70%) | 89 | (70%) |
| Men | 21.00 | (30%) | 39 | (30%) |
| Race/ethnic identity | ||||
| White | 52.00 | (75%) | 100 | (78%) |
| Black | 10 | (14%) | 13 | (10%) |
| Other | 7 | (10%) | 15 | (12%) |
| Study site | ||||
| A | 24 | (35%) | 42 | (33%) |
| B | 25 | (36%) | 45 | (35%) |
| C | 20 | (29%) | 41 | (32%) |
| BMI stratum | ||||
| 22.0–24.9 kg m−2 | 33 | (48%) | 60 | (47%) |
| 25.0–27.9 kg m−2 | 36 | (52%) | 68 | (53%) |
The table shows data for participants randomized to the AL control group and the CR treatment group. CALERIE included a total of N = 220 participants (AL n = 75, of whom n = 71 completed the study; CR n = 145, of whom n = 118 completed the study). The analysis sample was composed of CALERIE participants for whom DNAm data were available at baseline and at least one follow-up assessment (‘analysis sample’; N = 197; AL n = 69, CR n = 128).