Table 5.
Subgroups Analysis for the Associations of sUA with the Risk of SAAC
| sUA | Q1 | Q2 | Q3 | Q4 | P for Trend | P for Interaction |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |||
| Age | 0.056 | |||||
| < 60 | 1.00 | 0.245 (0.029, 2.058) | 0.472 (0.051, 4.332) | 0.011 (0.001, 1.437) | 0.112 | |
| ≥ 60 | 1.00 | 0.893 (0.396, 2.011) | 1.487 (0.628, 3.517) | 1.276 (0.507, 3.215) | 0.410 | |
| Sex | 0.051 | |||||
| Male | 1.00 | 0.395 (0.105, 1.485) | 0.632 (0.183, 2.187) | 0.601 (0.160, 2.257) | 0.822 | |
| Female | 1.00 | 1.134 (0.466, 2.758) | 1.819 (0.656, 5.044) | 1.573 (0.480, 5.153) | 0.298 | |
| Hypertension | 0.014 | |||||
| No | 1.00 | 0.298 (0.060, 1.488) | 0.121 (0.014, 1.064) | 0.504 (0.037, 6.845) | 0.214 | |
| Yes | 1.00 | 1.095 (0.453, 2.645) | 1.812 (0.731, 4.491) | 1.276 (0.484, 3.361) | 0.491 | |
| DM | 0.095 | |||||
| No | 1.00 | 0.702 (0.272, 1.810) | 1.369 (0.529, 3.540) | 1.115 (0.376, 3.306) | 0.532 | |
| Yes | 1.00 | 0.996 (0.250, 3.969) | 0.754 (0.165, 3.432) | 1.156 (0.208, 6.432) | 0.966 | |
| BMI | 0.488 | |||||
| < 30 kg/m2 | 1.00 | 0.755 (0.343, 1.663) | 1.087 (0.446, 2.647) | 0.815 (0.299, 2.218) | 0.864 | |
| ≥ 30 kg/m2 | 1.00 | 1.025 (0.119, 8.792) | 0.811 (0.113, 5.798) | 1.729 (0.175, 1.706) | 0.653 |
Notes: Analysis was adjusted for age, sex, race/ethnicity, education level, marital status, family poverty income ratio, hypertension, diabetes mellitus, smoke status, and drink status, physical activity, body mass index, waist circumference, mean energy intake, dietary phosphorus and calcium intake, hemoglobin, fast glucose, glycohemoglobin, aspartate aminotransferase, alanine aminotransferase, total bilirubin, gamma-glutamyl transferase, blood urea nitrogen, serum creatinine, estimated glomerular filtration rate, serum phosphorus and calcium, total cholesterol, triglyceride, and high-density lipoprotein-cholesterol.
Abbreviations: sUA, serum uric acid; SAAC, serve abdominal aortic calcification; Q1, 0.7–4.5 mg/dL; Q2, 4.6–5.4 mg/dL; Q3, 5.5–6.3 mg/dL; Q4, 6.4–11.3 mg/dL; OR, odd ratio; CI, confidence interval.