Table 1.
Baseline Demographic and Clinical Characteristics of the Study Population
| Characteristic | Total Population (n=154) | XEN Solo (n=37) | XEN+Phaco (n=117) | P value |
|---|---|---|---|---|
| Age, years | ||||
| Mean (SD) | 72.1 (8.9) | 69.6 (13.2) | 72.9 (9.7) | 0.4373a |
| 95% CI | 70.7–73.5 | 65.2–74.0 | 71.6–74.2 | |
| Sex, n (%) | ||||
| Female | 82 (53.2) | 20 (54.1) | 62 (53.0) | 1.0000b |
| Male | 72 (46.8) | 17 (45.9) | 55 (47.0) | |
| Eye, n (%) | ||||
| Right | 76 (49.4) | 14 (37.8) | 62 (53.0) | 0.1323b |
| Left | 78 (50.6) | 23 (62.2) | 55 (47.0) | |
| Diagnosis, n (%)c | ||||
| POAG | 112 (74.7) | 26 (72.2) | 86 (75.4) | 0.1194d |
| PEX | 22 (14.7) | 3 (8.3) | 19 (16.7) | |
| CNAG | 6 (4.0) | 2 (5.6) | 0 (0.0) | |
| PIG | 2 (1.3) | 0 (0.0) | 6 (5.3) | |
| Other | 8 (5.3) | 5 (13.9) | 3 (2.6) | |
| IOP, mmHg; | ||||
| Mean (SD) | 19.1 (5.0) | 21.2 (6.2) | 18.4 (4.3) | 0.0112a |
| 95% CI | 18.3–19.9 | 19.2–23.3 | 17.6 to 19.2 | |
| NOHM | ||||
| Mean (SD) | 2.1 (0.8) | 2.6 (0.7) | 1.9 (0.8) | <0.0001a |
| 95% CI | 1.9 to 2.2 | 2.3 to 2.8 | 1.8 to 2.0 | |
| NOHM, n (%) | ||||
| 1 | 44 (28.6) | 2 (5.4) | 42 (35.9) | <0.0001d |
| 2 | 61 (39.6) | 14 (37.8) | 47 (40.2) | |
| 3 | 45 (29.2) | 19 (51.4) | 26 (22.2) | |
| 4 | 4 (2.6) | 2 (5.4) | 2 (1.7) |
Notes: aMann–Whitney test. bFisher’s exact test. cDiagnosis data were available for 150 eyes. dChi-squared test for trend.
Abbreviations: SD, standard deviation; CI, confidence interval; POAG, primary open-angle glaucoma; PEX, pseudoexfoliative glaucoma; CNAG, chronic narrow-angle glaucoma; PIG, pigmentary glaucoma; IOP, intraocular pressure; NOHM, number of ocular hypotensive medications; Phaco, phacoemulsification.