Table 2.
Mean Changes in Intraocular Pressure (IOP) Over the Course of Follow-Up in the Eyes That Underwent XEN Alone (XEN) versus Those That Underwent XEN + Phacoemulsification (XEN+Phaco)
| Mean Change in IOP, mm Hg | Absolute Values | ||||||
| XEN | XEN+Phaco | Difference | |||||
| Mean | SE | Mean | SE | Mean (SE) | 95% CI | Pa | |
| Day 1 | −10.1 | 0.9 | −7.7 | 0.5 | −2.3 (1.1) | −4.5 to −0.4 | 0.0230 |
| Week 1 | −9.2 | 0.8 | −5.7 | 0.4 | −3.5 (0.9) | −5.3 to −1.8 | 0.0001 |
| Month 1 | −3.5 | 0.9 | −4.4 | 0.5 | 0.9 (1.0) | −1.1 to 2.9 | 0.3807 |
| Month 3 | −4.0 | 0.7 | −4.0 | 0.4 | 0.0 (0.8) | −1.6 to 1.5 | 0.9742 |
| Month 6 | −4.4 | 0.6 | −4.7 | 0.3 | 0.3 (0.7) | −1.0 to 1.6 | 0.6141 |
| Month 12 | −4.1 | 0.6 | −4.3 | 0.3 | 0.2 (0.7) | −1.1 to 1.5 | 0.7644 |
| Month 24 | −3.1 | 0.8 | −3.8 | 0.4 | 0.7 (0.9) | −2.5 to 1.1 | 0.4215 |
| Signification* | P<0.0001 | P<0.0001 | |||||
| Mean Change in IOP, mm Hg | Percentages | ||||||
| XEN | XEN+Phaco | Difference | |||||
| Mean | SE | Mean | SE | Mean (SE) | 95% CI | Pb | |
| Day 1 | −51.0 | 4.8 | −36.8 | 2.6 | −14.2 (5.7) | −25.5 to −3.0 | 0.0136 |
| Week 1 | −46.4 | 4.1 | −27.0 | 2.2 | −19.4 (4.9) | −29.0 to −9.8 | 0.0001 |
| Month 1 | −15.5 | 4.5 | −20.1 | 2.4 | 4.6 (5.3) | −5.8 to 15.0 | 0.3844 |
| Month 3 | −14.8 | 3.7 | −17.2 | 2.0 | 2.4 (4.4) | −6.2 to 11.0 | 0.5852 |
| Month 6 | −19.0 | 3.0 | −21.4 | 1.6 | 2.4 (3.5) | −4.7 to 9.4 | 0.5089 |
| Month 12 | −17.5 | 3.2 | −19.4 | 1.7 | 1.9 (3.7) | −5.5 to 9.3 | 0.6172 |
| Month 24 | −11.8 | 4.1 | −16.9 | 2.3 | 5.2 (4.9) | −4.5 to 14.8 | 0.2937 |
| Signification* | P<0.0001 | P<0.0001 | |||||
Notes: aBonferroni corrected. *Repeated measures ANCOVA and the Greenhouse–Geisser correction. bRepeated measures analysis of covariance (MANCOVA). The model included “Type of surgery” (XEN solo versus XEN+Phaco) as factor and age, preoperative IOP, and number of preoperative ocular hypotensive medications as covariates.
Abbreviations: IOP, intraocular pressure; SE, standard error; CI, confidence interval.