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. 2023 Apr 26;18:2141–2162. doi: 10.2147/IJN.S400195

Table 6.

Organ and Endpoint Toxicity Predicted Using ProTox-II

Compound Name Classification
Organ Toxicity (% Probability) Toxicity Endpoint (% Probability)
Hepatotoxicity Carcinogenicity Immunotoxicity Mutagenicity Cytotoxicity
Astragalin Inactive (82) Inactive (85) Inactive (64) Inactive (76) Inactive (69)
4-hydroxyphenyl acetic acid Inactive (55) Inactive (74) Inactive (99) Inactive (94) Inactive (83)
Caffeic acid Inactive (57) Active (78) Inactive (50) Inactive (98) Inactive (86)
Vernolic acid Inactive (66) Inactive (62) Inactive (98) Inactive (84) Inactive (64)