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. 2023 Apr 26;16:1193–1205. doi: 10.2147/DMSO.S407177

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© 2023 Ren et al.

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BA diminishes oxidative stress and inflammation in db/db mice. (A–C) SOD activity (A), CAT activity (B), and MDA level (C) in the kidneys of mice treated with various doses of BA (25, 50 and 100 mg/kg) or the same volume of normal saline for 12 weeks. (D–F) IL-1β secretion (D), IL-6 production (E), and TNF-α level (F) in the serum samples of mice in all groups at the end of the experiment. ***P<0.001 vs db/m mice; ^#P<0.05, ^##P<0.01, and ^###P<0.001 vs db/db model mice.

Abbreviations: SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α.