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BA alleviates HG-induced cell apoptosis via the S1P/NF-κB pathway. (A–D) HK-2 cells transfected with or without ov-S1P were stimulated with HG, HG+BA, or HG+BA+BAY11-7085. (A–D) p65 and p-p65 protein levels (A), cell viability (B), LDH activity (C), and cell apoptosis (D) in HK-2 cells treated as indicated. **P<0.01 and ***P<0.001 vs control; #P<0.05 and ##P<0.01 vs HG treatment; &P<0.05 and &&P<0.01 vs HG+BA treatment; ^P<0.05 and ^^P<0.01 vs ov-S1P+HG+BA treatment.
