Table 6.

Self-reported main symptoms besides fatigue and PEM, experienced by patients (N = 154).

Category	Description	Reported number
Sleep disturbance	Insomnia/sleep rhythm disturbances	24
	Unrefreshing sleep	16
	Increased need for sleep	12
Neurocognitiv impairment	Brain fog	61
	Concentration impairment	37
	Difficulty finding words	5
	Slurry speech	5
	Unspecified	2
Neuroendocrine manifestation	Recurrent sub-febrile/febrile episodes	11
	Poor thermoregulation	7
	Anxiety	7
	Feeling always cold	4
	Heat/cold intolerance	2
	Emotional sensibility	2
	Lack of appetite	1
	Sweating	1
Neurological Symptoms	Motor disturbance - Muscle weakness (unable to stand for long, difficulty walking, need of a walking stick of wheelchair, it feels like a “paresis”	86 78
	- Muscle cramps	2
	- Poorly coordinated movements	6
	Sensitivity to light/noise	29
	Tinnitus	8
	Visual impairments (blurry vision; inability to focus)	6
	Neuropathy (paresthesia)	4
	Seizure-like cramps	2
	Extremety numbness	1
	Tremors (hand, head)	1
	Feeling like having had a stroke on the left side	1
	Phantom smells (e.g. aceton)	1
Pain	Muscle/joint	98
	Headache/migranes/increased pressure behind the eyes or ears	39
	Thorax pains	1
Immunological manifestation	Feeling sick/flu-ish	18
	Regular bouts of temperature or fever	7
	Food allergies/intolerances	7
	Recurrent sore throat	4
	Recurrent swollen lymph nodes	4
	Recurrent sinusitis	3
	Drug intolerance	2
	Alcohol intolerance	1
	Mouth lesions/ulcers	1
	Susceptibility to infections	1
	Recurrent ear-nose-throat infections	1
Gastrointestinal manifestation	Diarrhea, constipation, bloating, vomiting	37
	Nausea	13
Autonomic manifestation	Dizzyness	26
	Orthostatic intolerance/POTS	10
	Palpitations/tachycardia	3
	Hypotension	2
	Bladder irritability	2
	Syncope	1
	Autonomous symptoms	1
	Eye irritation	1
Metabolic/Endocrine	Long menstrual cycle	1
	Metabolic HPU	1
Respiratory system	Short of breath, painful breathing	13