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. 2023 Apr 30;4(3):e252. doi: 10.1002/mco2.252

FIGURE 5.

FIGURE 5

Sleep deprivation‐resulting changes of immune cell and inflammatory cytokine profiles. (A) The statistics of immune cells (leukocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils) from routine blood detection after sleep deprivation, and (B) the proportions of various immune cells in total leukocytes. (C) Representative graphs of flow lymphocyte typing after sleep deprivation, and (D) statistics of the numbers and proportions of CD3+T, CD4+T, and CD8+T cells. (E) Heat map of inflammatory factor profiles after sleep deprivation. (F) Statistical analysis of pro‐inflammatory factors (interleukin [IL]‐2, IL‐6, IL‐8, IL‐12p70, IL‐17, TNF‐α, INF‐γ), c‐reactive protein (CRP) acute response protein and (G) anti‐inflammatory factors (IL‐4, IL‐10, IL‐13). (H) Correction analysis of IL‐8 and neutrophils. Data are presented as the mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; 15−32 individuals per group.