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. 2023 Apr 25;13(5):1171–1192. doi: 10.1007/s13555-023-00918-y

Table 8.

Changes in T and B lymphocytes in patients with atopic dermatitis, summary from other studies

Authors Summary
Czarnowicki et al. [56] Systemic expansion of transitional and chronically activated CD27(+) memory, plasmablast, and IgE-expressing memory subsets in children
Czarnowicki et al. [57]

↓ circulating CD19+CD20+ B cell in children

↑ CD3+ T cell counts in children

Looman et al. [62] Higher Th2, Treg, Treg-memory, CD27+ IgA+ memory B-cell numbers in children
Heeringa et al. [63] Maritime and alpine climates normalizes memory B cells, CD8+ T cells and Th2 cells
Czarnowicki et al. [65] Immune activation and cytokine polarization with chronological changes in the blood of infants and children with AD through adolescence
Yanaba et al. [66] CD19 expression in B cells plays a critical role in antigen-specific CD4(+) T-cell proliferation and T helper 2 and 17 responses in a murine model
Agrawall et al. [67]

↑ CD4+ helper T cells

T regulatory cells can convert to Th2 cells

Wang et al. [68]

↑ CD4+ helper T cells (Th2)

↑ production of IL-4 and IL-13

Szegedi et al. [69]

↑ CD4+ helper T cells (Th2)

↑ production of IL-31