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. 2023 Apr 17;14:1129544. doi: 10.3389/fphar.2023.1129544

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Copyright © 2023 Sun, Lei, Luo, Jiang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tumor mutation load and immune function in different risk population. (A) Waterfall plot of mutant genes in the high-risk group. (B) Waterfall plot of mutant genes in the low-risk group. (C) boxplot depict the tumor mutational burden of melanoma patients in the two groups. (D) The correlation analysis of risk score and tumor burden mutational in melanoma. (E) Heatmap of the association of 7 cuproptosis-related differential genes with immune cells. (F) Violin diagram of StromalScore, ImmuneScore and ESTIMATEScore compared between low-risk group and high-risk group. (G) Relevance analysis between risk score and stemness characteristics.