Table 1.
Summary of randomized clinical trial published from 2012 to 2022.
| Author (Year) [Ref] | Duration (month) |
Number and age of the Participants (Teeth) | Intervention group (final sample size) |
Caries incidence |
Sealant retention rate |
|---|---|---|---|---|---|
| Antonson et al. (2012) (44) | 24 | 39 children aged 5–9 (78 teeth) | Gp1: Resin sealant (27) | N/A | Gp1:41% |
| Gp2: Glass ionomer sealant (27) | Gp2:44% | ||||
| Bhatia et al. (2012) (45) | 12 | 17 children aged 6–8 (68 teeth) | Gp1: Hydrophilic resin sealant (34) | N/A | Gp1:24% |
| Gp2: Hydrophobic resin sealant (34) | Gp2:18%* | ||||
| Ulusu et al. (2012) (46) | 24 | 173 children aged 7–15 (346 teeth) | Gp1: Glass ionomer sealant (139) | Gp1:3% | Gp1:14% |
| Gp2:5% | Gp2:21%* | ||||
| Gp2: Resin Sealant (137) | |||||
| Bhat et al. (2013) (47) | 12 | 80 children aged 6–9 (320 teeth) | Gp1: Resin sealant with bond (76) | G1:3% | Gp1:82% |
| Gp2: Resin sealant (76) | Gp2:3% | Gp2:72% | |||
| Gp3: Hydrophilic resin sealant (76) | Gp3:3% | Gp3:80% | |||
| Gp4: Glass ionomer sealant (76) | Gp4:7% | Gp4:21% | |||
| * Gp1/2/3 > 4 | |||||
| Chen and Liu (2013) (48) | 24 | 61 children aged 6–9 (158 teeth) | Gp1: Glass ionomer sealant (75) | Gp1:8% | Gp1:36% |
| Gp2: Resin sealant (75) | Gp2:8% | Gp2:72%* | |||
| Kumaran (2013) (49) | 12 | 40 children aged 7–10 (160 teeth) | Gp1: Filled resin sealant 1 (38) | N/A | Gp1:66% |
| Gp2: Unfilled resin sealant (38) | Gp2:42% | ||||
| Gp3: Filled resin sealant 2 (38) | Gp3:29% | ||||
| Gp4: Glass ionomer sealant (38) | Gp4:32% | ||||
| * Gp1 > 2/3/4 | |||||
| Hasanuddin et al. (2014) (50) | 12 | 80 children aged 7–10 (160 teeth) | Gp1: Resin sealant (80) | Gp1:0% | Gp1:68% |
| Gp2: Glass ionomer sealant (80) | Gp2:0% | Gp2:24%* | |||
| Khatri et al. (2015) (51) | 12 | 34 children aged 6–9 (68 teeth) | Gp1: Hydrophilic resin sealant (32) | Gp1:6% | Gp1:72% |
| Gp2: Resin sealant (32) | Gp2:16% | Gp2:50%* | |||
| Reddy et al. (2015) (26) | 12 | 56 children aged 6–9 (224 teeth) | Gp1: Filled resin sealant (112) | N/A | Gp1:54% |
| Gp2: Unfilled resin sealant (112) | Gp2:64% | ||||
| Gonçalves et al. (2016) (52) | 6 | 31 children aged 6–8 (114 teeth) | Gp1: Resin-modified glass ionomer sealant (33) | Gp1:3% | Gp1:52% |
| Gp2: Resin sealant (35) | Gp2:3% | Gp2:89% | |||
| Gp3: No sealant (28) | Gp3:36% | Gp3: N/A | |||
| * Gp1/2 > 3 | * Gp2 > 1 | ||||
| Haznedaroğlu et al. (2016) (53) | 48 | 40 children aged 7–10 (160 teeth) | Gp1: Glass ionomer sealant (40) | Gp1:10% | Gp1:8% |
| Gp2: Resin sealant (56) | Gp2:21% | Gp2:39%* | |||
| Al-Jobair et al. (2017) (54) | 18 | 42 children aged 6–9 (168 teeth) | Gp1: Glass ionomer sealant (70) | Gp1:31% | Gp1:26% |
| Gp2: Resin sealant (70) | Gp2:27% | Gp2:33% | |||
| Askarizadeh et al. (2017) (55) | 12 | 23 children aged 6–9 (92 teeth) | Gp1: Resin sealant (40) | Gp1:3% | Gp1:63% |
| Gp2: Hydrophilic resin sealant (40) | Gp2:8% | Gp2:60% | |||
| Liu et al. (2018) (56) | 60 | 419 children aged 7–9 (664 teeth) | Gp1: Resin sealant (172) | Gp1:13% | N/A |
| Gp2: Glass ionomer sealant (178) | Gp2:23% | ||||
| Gp3: No sealant (165) | Gp3:35% | ||||
| * Gp1 > 2>3 | |||||
| Ntaoutidou et al. (2018) (57) | 18 | 81 children aged 6–12 (218 teeth) | Gp1: Giomer sealant (87) | Gp1:15 % | Gp1:7% |
| Gp2: Resin sealant (89) | Gp2: 6%* | Gp2:70%* | |||
| Siripokkapat et al. (2018) (58) | 12 | 140 children aged 2.5–5 (280 teeth) | Gp1: Resin sealant (116) | Gp1:8% | Gp1:72% |
| Gp2: Giomer sealant (116) | Gp2:20%* | Gp2:15%* | |||
| Alsabek et al. (2019) (40) | 6 | 40 children aged 6–9 (80 teeth) | Gp1: Hydrophilic resin sealant (40) | N/A | Gp1:85% |
| Gp2: Glass ionomer sealant (40) | Gp2:63%* | ||||
| Mathew et al. (2019) (59) | 12 | 50 children aged 6–8 (100 teeth) | Gp1: Resin-modified glass ionomer sealant (50) | Gp1:2% | Gp1:78% |
| Gp2: Resin sealant (50) | Gp2:0% | Gp2:88% | |||
| Prathibha et al. (2019) (60) | 12 | 120 children aged 7–9 (240 teeth) | Gp1: Glass ionomer sealant (111) | Gp1:9% | Gp1:51% |
| Gp2: Resin sealant (111) | Gp2:5% | Gp2:76%* | |||
| Jaafar et al. (2020) (61) | 6 | 45 children aged 8–12 (90 teeth) | Gp1: Resin sealant (45) | N/A | Gp1:76% |
| Gp2: Glass ionomer sealant (45) | Gp2:49%* | ||||
| Mohapatra et al. (2020) (62) | 6 | 30 children aged 12–15 (120 teeth) | Gp1: Resin sealant (44) | N/A | Gp1:23% |
| Gp2: Hydrophilic resin sealant (44) | Gp2:11% | ||||
| Beresescu et al. (2022) (63) | 24 | 28 children age 6–8 (112 teeth) | Gp1: Hydrophilic resin sealant (56) | Gp1:9% | Gp1:79% |
| Gp2: Resin sealant (56) | Gp2:5% | Gp2:80% | |||
| Haricharan et al. (2022) (64) | 24 | 180 children aged 6–12 (360 teeth) | Gp1: Resin sealant (180) | Gp1:7% | Gp1:39% |
| Gp2: Glass ionomer sealant (180) | Gp2:11% | Gp2:32% | |||
| Özgür et al. (2022) (65) | 12 | 57 children aged 6–12 (136 teeth) | Gp1: Resin sealant (50) | Gp1:0% | Gp1:68% |
| Gp2: Giomer sealant (50) | Gp2:0% | Gp2:8%* | |||
| Reic et al. (2022) (66) | 24 | 80 children aged 6–13 (253 teeth) | Gp1: Glass ionomer sealant (51) | Gp1:27% | Gp1:19% |
| Gp2: Filled resin sealant 1 (66) | Gp2:11% | Gp2:46% | |||
| Gp3: Unfilled resin sealant (58) | Gp3:24% | Gp3:21% | |||
| Gp4: Filled resin sealant 2 (58) | Gp4:19% | Gp4:47% | |||
| * Gp2 > 1/3/4 | * Gp2/4 > 1/3 | ||||
| Singh et al. (2022) (67) | 12 | 45 children aged 3–5 (180 teeth) | Gp1: Giomer sealant (90) | Gp1:14% | Gp1:26% |
| Gp2: Hydrophilic resin sealant (90) | Gp2:15% | Gp2:76%* | |||
| Uzel et al. (2022) (68) | 18 | 50 children aged 7–12 (200 teeth) | Gp1: No sealant (35) | Gp1:26% | Gp1:N/A |
| Gp2: Resin sealant 1 (32) | Gp2:9% | Gp2:52% | |||
| Gp3: Resin sealant 2 (33) | Gp3:3% | Gp3:24% | |||
| Gp4: Glass ionomer sealant (33) | Gp4:3% | Gp4:18% | |||
| * Gp3/4 > 1 | * Gp1 > 2/3 |
*
Statistically significant.