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. 2023 Apr 17;14:1164553. doi: 10.3389/fmicb.2023.1164553

Table 3.

Maternal variables and time elapsed associate with the stability of breast milk microbiota and infant gut microbiota over time.

Breast Milk OR (95% CI)a,b
Cluster switching degree 1 Clustering switching degree 2
Days postpartum of last sample collected 1.03 (1.00–1.07) 1.16 (1.11–1.22)
Maternal pre-pregnancy BMI 1.86 (0.83–4.17) 4.55 (2.22–9.36)
Maternal age 0.61 (0.32–1.15) 2.14 (1.05–4.36)
Prenatal antibiotics 915.08 (0.08–11,075,210) 1051930.57 (73.01–15,156,890,000)
aModel adjusted for days postpartum of last sample collected, maternal pre-pregnancy BMI, maternal age, and prenatal antibiotic exposure
bNo cluster switching as reference level
Infant Stool OR (95% CI)a,b
Cluster switching degree 1 Clustering switching degree 2
Infant age at last sample collection 0.98 (0.95–1.01) 1.07 (1.02–1.12)
Maternal age 0.68 (0.45–1.02) 0.75 (0.53–1.06)
Prenatal antibiotics 167.79 (1.70–16,598) 4.40 (1.04–185.50)
a

Model adjusted for days postpartum of last sample collected, maternal age, and prenatal antibiotic exposure.

b

No cluster switching as reference level.