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. 2023 Apr 17;10:1175848. doi: 10.3389/fvets.2023.1175848

Table 1.

Structure and structure-activity-relationship of polysaccharide from Atractylodes macrocephala Koidz.

Type Extraction method Monosaccharide composition Molecular weight/kDa Structure characteristics Function Reference
Atractylodes macrocephala Koidz Ultrasonicassisted enzymatic extraction - - - Anti-oxidation (23)
Atractylodes macrocephala Koidz Alcohol precipitation Gal: Ara: Glc=1.00: 1.50: 5.00 4.10 kDa Three α-pyranose residues, α D Glupα D Galp and α L Araf Anti-tumor (25)
Atractylodes macrocephala Koidz Hot water extraction Man: GalA: Glc: Gal: Ara=1.00: 8.58: 27.28: 3.68: 4.99 4.35 kDa → 3-β-D-Glcp-(1 → , → 3,6-β-D-Glcp-(1 → , → 6-β-D-Glcp-(1 → ,T-β-D-Glcp, → 4-α-GalpA-(1 → , → 4-α-GalpA-OMe-(1 → , → 5-α-Araf-(1 → , → 4,6-β-manp-(1 → and → 4-β-Galp-(1 → Immunomodulation (26)
Atractylodes macrocephala Koidz Hot water extraction Rha: Ara: Gal: GalA=1.00: 1.84: 0.74: 4.23 161.90 kDa t-Araf, 1,5-Araf, 1,3,5-Araf, 1,2-Rhap, 1,2,4-Rhap, t-Galp, 1,4-Galp, 1,3,4-Galp, 1,4,6-Galp and 1,4-GalpA residues Immunomodulation (27)
Atractylodes macrocephala Koidz Alcohol precipitation Ara: Glc=1.00: 4.57 2.10 kDa Pyranose rings and α-type and β-type glycosidic lin kages Anti-tumor (28)
Atractylodes macrocephala Koidz Hot water extraction Fuc: Ara: Gal: Glc: Xyl: Man: Fru: GalA=0.07: 0.99: 1.23: 6.70: 0.01: 0.09: 0.12: 0.76 4.75 kDa - Anti-inflammation (29)
Atractylodes macrocephala Koidz Water extraction Glc: Gal: Man: Ara: Rha=3.00: 2.50: 1.30: 3.50: 1.00 - - Hypoglycemic (30)
Atractylodes macrocephala Koidz Alcohol precipitation Glc: Man=0.58: 0.42 2.82 kDa (1 → 3)-Glc residues. (1 → 6)-linked monosaccharide backbone Hypolipidemic (31)

Gal, galactose; Ara, arabinose; Glc, glucose; Man, mannose; GalA, galacturonic acid; Rha, rhamnose; Fuc, fucose; Xyl, xylose; Fru, fructose; GlcA, glucuronic acid; GlcN, glucosamine; GalN, galactosamine; Rib, ribose; Myo, myo-inositol; ManA, mannuronic acid.