FIGURE 7.

Effect of HJ on the macroscopic and histological changes of piglets infected with PEDV. Piglets received HJ (1.28 g/kg) by oral administration for 6 days before PEDV-G2 (5 mL DMEM containing l0⁵ PFU) infection. The intestinal microscopic lesions of piglets in the model group (A) and the treated group (B) were recorded before sampled. The thin-wall intestinal tracts containing undigested food were indicated by blue arrows. The histological changes of intestine of piglets in the model group (C) and the treated group (D) were analyzed by hematoxylin-eosin (HE) staining. The damage and shedding of intestinal villi were indicated by red arrows. The height of villi (E) and crypt (F) in HE staining were measured to evaluate the growth and development of intestinal. Data are represented as mean ± SD, n = 3. *, and p < 0.05 was considered statistically significant compared with the model group.