Table 2.
Echocardiographic characteristics.
| Echocardiographic characteristics | All patients (n = 132) | Normal baseline RV-PA coupling | Impaired baseline RV-PA coupling | p-value |
|---|---|---|---|---|
| RVFWLS/PASP ≥0.63 (n = 65) | RVFWLS/PASP <0.63 (n = 67) | |||
| Aortic stenosis severity | ||||
| Vmax, m/s | 4.67 ± 0.8 | 4.8 ± 0.8 | 4.6 ± 0.8 | 0.106 |
| Mean gradient, mmHg | 57.6 ± 19.3 | 59.7 ± 19.4 | 55.6 ± 19.3 | 0.233 |
| AVAi, cm2/m2 | 0.4 ± 0.2 | 0.44 ± 0.2 | 0.37 ± 0.1 | 0.008 |
| Bicuspid valve | 19 (14.4%) | 5 (7.7%) | 14 (20.9%) | 0.031 |
| Aortic regurgitation | 1.2 ± 0.7 | 1.3 ± 0.7 | 1.2 ± 0.7 | 0.742 |
| Left ventricle | ||||
| LVEF, % | 51.8 ± 12.2 | 55.0 ± 7.9 | 48.6 ± 14.9 | 0.001 |
| LV-GLS, % | −12.4 ± 4.3 | −14.2 ± 3.9 | −10.5 ± 3.7 | <0.001 |
| LVMi, g/m2 | 180.3 ± 50.9 | 174 ± 47 | 187 ± 53 | 0.154 |
| E/A | 1.2 ± 0.8 | 0.84 ± 0.4 | 1.8 ± 0.9 | <0.001 |
| Mitral regurgitation | 1.3 ± 0.6 | 1.28 ± 0.6 | 1.27 ± 0.6 | 0.934 |
| Left atrium | ||||
| LAAi, cm2/m2 | 15.2 ± 3.3 | 14.2 ± 2.4 | 16.3 ± 3.6 | <0.001 |
| LAVi, ml/m2 | 55.2 ± 19.0 | 49.3 ± 13.4 | 61.3 ± 21.6 | <0.001 |
| LA-GLS, % (LAɛ) | 12.4 ± 6.9 | 16.1 ± 5.9 | 8.6 ± 5.6 | <0.001 |
| Right ventricle | ||||
| TAPSE, cm | 2.0 ± 0.4 | 2.2 ± 0.4 | 1.9 ± 0.4 | <0.001 |
| S`RV, cm/s | 10.4 ± 2.8 | 11.5 ± 2.5 | 9.4 ± 2.6 | <0.001 |
| FAC, % | 0.59 ± 0.3 | 42.6 ± 6.5 | 38.9 ± 9.1 | 0.009 |
| PASP, mmHg | 40.5 ± 15 | 30.9 ± 8.4 | 49.2 ± 15.1 | <0.001 |
| PAPm, mmHg | 26.3 ± 9.2 | 20.9 ± 5.2 | 32.0 ± 9.2 | <0.001 |
| RA, mm | 0.41 ± 0.1 | 33.8 ± 6.7 | 41.4 ± 8.5 | <0.001 |
| RV, mm | 37.7 ± 8.4 | 32.0 ± 4.7 | 36.6 ± 6.4 | <0.001 |
| Tricuspid regurgitation | 0.98 ± 0.87 | 0.85 ± 0.83 | 1.2 ± 0.90 | 0.014 |
| RV-GLS, % | 34.3 ± 6.1 | −21.2 ± 4.3 | −13.6 ± 4.9 | <0.001 |
| RV-FWLS, % | −17.4 ± 6.0 | −27.0 ± 4.9 | −16.9 ± 6.1 | <0.001 |
| RV-IVS, % | −22.0 ± 7.5 | −13.4 ± 6.1 | −8.6 ± 5.7 | <0.001 |
Values are mean ± SD, n (%), or median (interquartile range). Vmax, maximum aortic velocity; AVA, aortic valve area; AVAi, aortic valve area index; LVEF, left ventricle ejection fraction; LV-GLS, left ventricle global longitudinal strain; LA, left atrium; LAAi, LA area index; LAVi, LA volume index; LVMi, LV mass index; LA-GLS, LA global longitudinal strain; TAPSE, tricuspid annular plane systolic excursion; S`RV, peak systolic myocardial velocity at the lateral site of the tricuspid annulus; PASP, systolic pulmonary artery pressure; PAPm, mean pulmonary artery pressure; FAC, right ventricle fractional area change; RA, right atrium; RV, right ventricle; RV-GLS, RV global longitudinal strain; RV-FWLS, RV free wall longitudinal strain; RV-IVS, RV interventricular septum strain.