Table 6.
Predictors of MACE and mortality (Cox regression analysis).
| Univariable analysis | MACE | Death | ||||
|---|---|---|---|---|---|---|
| Baseline parameters | HR | 95% CI | p-value | HR | 95% CI | p-value |
| Atrial fibrillation | 2.18 | 1.14–4.16 | 0.018 | 2.27 | 1.02–5.07 | 0.044 |
| LAVi | 1.01 | 0.99–1.02 | 0.110 | 1.02 | 0.99–1.03 | 0.059 |
| LAVi > 44* | 2.40 | 1.01–5.73 | 0.049 | 3.11 | 0.94–10.4 | 0.065 |
| LA-GLS | 0.96 | 0.91–1.01 | 0.110 | 0.96 | 0.90–1.02 | 0.160 |
| LA-GLS > 14* | 0.42 | 0.19–0.91 | 0.027 | 0.31 | 0.11–0.91 | 0.032 |
| LAAi | 1.07 | 0.99–1.16 | 0.097 | 1.10 | 1.00–1.21 | 0.047 |
| LAAi > 14* | 2.67 | 1.23–5.82 | 0.013 | 2.67 | 1.20–10.2 | 0.021 |
| PASP | 1.03 | 1.01–1.05 | 0.007 | 1.03 | 1.00–1.05 | 0.030 |
| PASP > 60* | 3.06 | 1.39–6.71 | 0.005 | 3.63 | 1.44–9.15 | 0.006 |
| TAPSE/PASP | 0.26 | 0.66–1.06 | 0.061 | 0.50 | 0.10–2.55 | 0.401 |
| TAPSE/PASP < 0.36* | 3.12 | 1.64–5.92 | 0.001 | 2.41 | 1.07–5.42 | 0.034 |
| RV-FWLS | 1.03 | 0.99–1.08 | 0.128 | 1.05 | 0.99–1.10 | 0.082 |
| RV-FWLS/PASP | 3.77 | 1.25–11.4 | 0.019 | 5.51 | 1.32–23.0 | 0.019 |
| RV-FWLS/PASP < 0.63* | 3.27 | 1.54–6.97 | 0.002 | 7.39 | 2.19–24.9 | 0.001 |
| Multivariable analysis | MACE | Death | ||||
| RV-FWLS/PASP | 4.14 | 1.37–12.5 | 0.012 | 5.97 | 1.44–24.8 | 0.014 |
MACE, major adverse cardiac events; LAVi, LA volume index; LAAI, LA area index; LA-GLS, LA global longitudinal strain; TAPSE, tricuspid annular plane systolic excursion; PAPS, systolic pulmonary artery pressure; PAPm, mean pulmonary artery pressure; RV-FWLS, RV free wall longitudinal strain; RV-GLS, RV global longitudinal strain. Multivariable analysis (Backward Wald)—variables: atrial fibrillation, LAVi, LAAi, LA-GLS, RV-FWS/PSAP.
*Cut-off values determined by ROC analysis.