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. 2023 Apr 17;11:1119163. doi: 10.3389/fpubh.2023.1119163

Table 2.

Univariate and multivariate logistic regression of characteristics for association with vaccination status.

Univariate logistic regression analysis 95% CI for OR Multivariate logistic regression analysis*** 95% CI for OR
OR Lower Upper Value of p OR Lower Upper Value of p
Sociodemographic variables
Age in years
25–39 Ref.
40–49 1.024 0.789 1.328 0.859
50–59 0.926 0.715 1.198 0.558
60–69 0.930 0.697 1.240 0.621
70–79 0.713 0.472 1.074 0.107
80+ 0.523 0.249 1.056 0.076
Missing*
Educational attainment
Undergraduate Ref.
Postgraduate 1.151 0.900 1.474 0.264
High school and below 0.870 0.744 1.016 0.078
Monthly household income per capita, yuan
2,000–5,000 Ref.
<2000 1.063 0.773 1.461 0.707
5,000-10,000 1.173 0.981 1.403 0.081
>10,000 1.282 1.062 1.548 0.010
Administrative regions
East Ref.
North 0.977 0.749 1.274 0.861
Northeast 1.131 0.788 1.624 0.505
Central 1.063 0.636 1.780 0.815
South 2.090 0.894 5.291 0.100
Southwest 0.605 0.232 1.489 0.283
Northwest 0.894 0.512 1.558 0.693
Living area
Urban Ref.
Rural 1.023 0.765 1.369 0.879
Work status
Unemployed Ref. Ref.
Employed 1.363 1.062 1.751 0.015 1.783 1.118 2.842 0.015
Retired 0.866 0.675 1.110 0.256 1.049 0.661 1.666 0.839
Student 2.121 0.201 45.916 0.541 390185542.547 0.000 . 1.000
Have children under age 18
No Ref.
Yes 0.861 0.740 1.001 0.051
Health and disease status
Self-perceived health
Bad Ref.
General 0.448 0.244 0.797 0.007
Good 0.536 0.296 0.940 0.034
Recent breast cancer-related treatment
Cytotoxic therapy** Ref. Ref.
Endocrine therapy 0.478 0.400 0.570 <0.001 0.531 0.376 0.749 <0.001
Traditional Chinese medicine 0.489 0.313 0.757 0.001 0.932 0.389 2.233 0.875
No treatment 0.858 0.697 1.055 0.147 1.124 0.745 1.693 0.578
Missing*
Time after surgery
<1 year Ref. Ref.
1–3 years 0.263 0.210 0.329 <0.001 0.277 0.176 0.436 <0.001
3–5 years 0.292 0.228 0.373 <0.001 0.277 0.170 0.451 <0.001
> = 5 years 0.340 0.270 0.427 <0.001 0.282 0.179 0.443 <0.001
Missing*
History of food or drug allergies
No Ref. Ref.
Yes 0.529 0.442 0.632 <0.001 0.579 0.417 0.804 0.001
History of other vaccine allergies
No Ref.
Yes 0.317 0.211 0.467 <0.001
Stage at diagnosis
0 Ref. Ref.
I 3.214 2.255 4.598 <0.001 2.008 1.124 3.590 0.019
II 1.130 0.803 1.594 0.485 1.062 0.637 1.772 0.817
III 0.947 0.666 1.349 0.760 0.801 0.472 1.360 0.411
IV
Missing*
Histology
Carcinoma in situ Ref.
Invasive ductal carcinoma 0.893 0.682 1.167 0.408
Invasive lobular carcinoma 1.134 0.673 1.923 0.639
Others 0.927 0.626 1.371 0.704
Missing*
Histological grade
G1 Ref.
G2 1.129 0.841 1.518 0.420
G3 1.159 0.847 1.586 0.358
Missing*
Molecular subtype
Luminal A Ref.
Luminal B 0.884 0.714 1.095 0.259
HER2 over-expression subtype 0.945 0.657 1.360 0.762
Basal-like 0.985 0.702 1.385 0.933
Missing*
Variables related to COVID-19
History of COVID-19 infection
No Ref.
Yes, no symptoms 0.991 0.039 25.078 0.995
Yes, mild symptoms 0.991 0.183 5.363 0.991
Yes, severe symptoms 1.321 0.291 6.719 0.716
Worried about infection
No Ref.
Yes 1.094 0.933 1.282 0.270
Have you consulted healthcare workers about COVID-19 vaccines?
No Ref.
Yes, my questions were answered. 1.035 0.881 1.215 0.676
Yes, my questions were not answered. 0.803 0.651 0.989 0.039
Think vaccines can provide protection
No Ref. Ref.
Yes 1.549 1.285 1.867 <0.001 1.774 1.170 2.690 0.007
Perceptions on vaccine safety
General Ref. Ref.
Safe 1.719 1.459 2.027 <0.001 2.074 1.513 2.843 <0.001
Very safe 2.963 2.229 3.967 <0.001 4.251 2.452 7.369 <0.001
Not safe 1.506 1.145 1.980 0.003 2.075 1.185 3.635 0.011
Very unsafe 5.024 3.038 8.699 <0.001 5.609 1.807 17.407 0.003

Values in red indicates these are statistically significant

OR, odds ratio; CI, confidence interval.

*

Missing values were not included for statistical analysis.

**

Chemotherapy/radiotherapy/targeted therapy, with/without endocrine therapy or traditional Chinese medicine.

***

Intercept = 0.15 (p = 0.722); Cox & Snell R Square = 0.192; Nagelkerke R Square = 0.256.