Table 1.
Demographic and Clinical Characteristics of Organ Donors that Underwent Organ Recovery Procedures in Organ Procurement Organization-Based Facilities Versus Acute-Care Hospitals.
| Organ recovery procedure location | Organ procurement organization-based recovery facility | Acute-care hospital | P-value |
|---|---|---|---|
| N (%) | N (%) | ||
| Deceased donors | 2590 (51.7) | 2420 (48.3) | |
| Donor in hospital with a transplant programa,b | 693 (26.8) | 1165 (48.1) | <.001 |
| Donor demographic characteristics | |||
| Mean (SD) | Mean (SD) | ||
| Age at organ recovery procedure, years | 43.1 (14.5) | 43.2 (15.3) | .66 |
| N (%) | N (%) | ||
| Sex, female | 1059 (40.9) | 948 (39.2) | .22 |
| Race a | |||
| White | 1770 (68.3) | 1372 (56.7) | <.001 |
| Black | 527 (20.4) | 405 (16.7) | |
| Hispanic | 236 (9.1) | 523 (21.6) | |
| Asian | 38 (1.5) | 81 (3.4) | |
| Other or unknown | 19 (0.7) | 39 (1.6) | |
| Donation year | |||
| 2017 | 223 (61.9) | 137 (38.1) | <.001 |
| 2018 | 431 (55.5) | 346 (44.5) | |
| 2019 | 615 (43.7) | 792 (56.3) | |
| 2020 | 801 (50.6) | 782 (49.4) | |
| 2021 (Jan 1 - Jun 30) | 520 (58.9) | 363 (41.1) | |
| Donor clinical characteristics | |||
| Median [IQR] | Median [IQR] | ||
| Donor height, cm | 173 [165, 180] | 170 [164, 178] | <.001 |
| Donor weight, kg | 81 [69, 97] | 81 [69, 97] | .67 |
| Mechanism of death a | N (%) | N (%) | |
| Intracranial hemorrhage/stroke | 732 (28.3) | 773 (31.9) | <.001 |
| Blunt injury | 425 (16.4) | 455 (18.8) | |
| Drug intoxication | 481 (18.6) | 299 (12.4) | |
| Cardiovascular | 448 (17.3) | 473 (19.6) | |
| Gunshot | 242 (9.3) | 198 (8.2) | |
| Asphyxiation | 122 (4.7) | 106 (4.4) | |
| Natural causes | 76 (2.9) | 37 (1.5) | |
| Drowning | 9 (0.3) | 9 (0.4) | |
| Seizure | 30 (1.2) | 25 (1.0) | |
| Other or unknown | 25 (1.0) | 45 (1.9) | |
| Comorbid disease a | |||
| Diabetes, any duration | 361 (13.9) | 368 (15.2) | .20 |
| Hypertension | 984 (38.0) | 896 (37.0) | .05 |
| History of coronary artery disease | 263 (10.2) | 166 (6.9) | <.001 |
| History of cancer | 74 (2.9) | 89 (3.7) | .10 |
| History of tobacco use | 634 (24.5) | 498 (20.6) | .001 |
| History of cocaine use | 613 (23.7) | 492 (20.3) | .004 |
| History of intravenous drug use | 437 (16.9) | 283 (11.7) | <.001 |
| History of other drug use | 1394 (53.8) | 1114 (46.0) | <.001 |
| Organ risk and function indicators | |||
| United States Public Health Service risk donora,c | 754 (29.1) | 659 (27.2) | .14 |
| HCV nucleic acid test positive | 202 (7.8) | 152 (6.3) | .04 |
| Terminal serum creatinine, mg/dL | Median [IQR] | Median [IQR] | |
| All donors | 1.2 [0.8, 2.0] | 1.3 [0.9, 2.2] | <.001 |
| Donors with kidney(s) recovered for transplant | 1.1 [0.8, 1.8] | 1.2 [0.8, 2.0] | <.001 |
| Kidney donor profile indexa,d | Mean (SD) | Mean (SD) | |
| All donors | 0.50 (0.30) | 0.51 (0.31) | .16 |
| Donors with kidney(s) recovered for transplant | 0.48 (0.29) | 0.49 (0.30) | .06 |
Abbreviation: HCV, hepatitis C virus.
a
As defined by OPTN. 16
b
For donors in facilities, transplant program at referring acute-care hospital.
c
US Public Health Service infectious disease transmission guidelines. 19
d
As calculated by the Organ Procurement and Transplantation Network, reference population 2020. 18