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. 2023 Apr 16;15(4):297–308. doi: 10.4253/wjge.v15.i4.297

Table 3.

Causes of gastrointestinal bleeding in children in relation to age group

Causes a Age group (yr)
Total, n (%) P value b
0-4, n = 58 (23.2)
5-9, n = 82 (32.8)
10-18, n = 107 (42.8)
Inflammatory bowel disease 10 (17.2) 27 (32.9) 40 (37.4) 77 (30.8) 0.026
Gastritis 16 (27.6) 23 (28) 31 (29) 70 (28) 0.980
Unclear cause (normal) 3 (5.2) 4 (4.9) 17 (15.9) 24 (9.6) 0.017
Gastroenteritis 7 (12.1) 9 (11) 6 (5.6) 22 (8.8) 0.275
Duodenal ulcer 5 (8.6) 4 (4.9) 11 (10.3) 20 (8) 0.397
Esophagitis 4 (6.9) 5 (6.1) 6 (5.6) 15 (6) 0.947
Rectal polyp 6 (10.3) 5 (6.1) 4 (3.7) 15 (6) 0.237
Anal fissure 1 (1.7) 5 (6.1) 5 (4.7) 11 (4.4) 0.461
Peptic ulcer 4 (6.9) 4 (4.9) 1 (0.9) 9 (3.6) 0.114
Colonic ulcers 2 (3.4) 5 (6.1) 2 (1.9) 9 (3.6) 0.305
Rectal ulcer 0 (0) 2 (2.4) 7 (6.5) 9 (3.6) 0.078
Intestinal nodular lymphoid hyperplasia 4 (6.9) 4 (4.9) 0 (0) 8 (3.2) 0.034
Foreign body ingestion 6 (10.3) 1 (1.2) 0 (0) 7 (2.8) < 0.0001
Esophageal varices 4 (6.9) 0 (0) 2 (1.9) 6 (2.4) 0.029
Esophageal ulcer 2 (3.4) 1 (1.2) 2 (1.9) 5 (2) 0.646
Meckel’s diverticulum 1 (1.7) 2 (2.4) 1 (0.9) 4 (1.6) 0.717
Mallory Weiss syndrome 1 (1.7) 2 (2.4) 0 (0) 3 (1.2) 0.291
Hemorrhoids 1 (1.7) 0 (0) 1 (0.9) 2 (0.8) 0.524
Duodenal varices 1 (1.7) 0 (0) 0 (0) 1 (0.4) 0.195
Colonic angiodysplasia 0 (0) 0 (0) 1 (0.9) 1 (0.4) 0.518
CMPA 1 (1.7) 0 (0) 0 (0) 1 (0.4) 0.195
a

Some patients may have more than one cause.

b

Pearson χ2. Data are presented as number and percentage. P value < 0.05 was considered statistically significant. CMPA: cow’s milk protein allergy.