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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: ACS Nano. 2023 Feb 6;17(4):3610–3619. doi: 10.1021/acsnano.2c10371

Figure 1. Dual-enhanced plasmonic ultrasensitive sensing (DuPLUS) for multiplexed cytokine analysis.

Figure 1.

(a) Schematic of DuPLUS assay integrating a plasmon-enhanced chemifluorescence assay with tyramide signal amplification. (b) Schematic of a line-scanning laser imaging system to measure multiple sensing arrays in a single chip. (c) Zoomed-in schematic showing scanning of sensing arrays using a line laser indicated by a white dashed circle in (b). A linear actuator moves a chip along the x-direction to scan multiple sensing arrays. The inset shows the scanned fluorescence image of multiplexed cytokine measurement. Scale bar: 2 mm.