Figure 8.

Cartoon representation of the complex between Bothrops pirajai PrTX-II and a fatty acid (tridecanoic acid) (PDB 1QLL).⁷⁷ A close-up view of the binding site of PrTX-II, with the fatty acid molecule stabilized by a hydrogen bond with the Cys29–Gly30 peptide bond, which is hyperpolarized by the Lys122, increasing its affinity for the fatty acid. The Ca²⁺ binding loop interactions with the Nε atom of the Lys49 residue are also shown. PyMOL molecular graphics software package was used to generate the representations.