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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Abdom Radiol (NY). 2022 Jun 16;47(8):2770–2782. doi: 10.1007/s00261-022-03572-8

Table 2.

Predictive performance of qualitative assessment of each reader (Reader 1, senior; Reader 2, junior), and when qualitative assessment is combined with the integrated radiomics classifier (n = 91). The results are from the external validation set.

Classifier Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI)
Reader 1 38% (9%–76%)
3/8		 98% (87%–100%)
41/42		 75% (19%–99%)
3/4		 89% (76%–96%)
41/46
Reader 2 50% (16%–84%)
4/8		 90% (77%–97%)
38/42		 50% (16%–84%)
4/8		 90% (77%–97%)
38/42
Model A + B + R1 38% (9%–76%)
3/8		 95% (84%–99%)
40/42		 60% (15%–95%)
3/5		 89% (76%–96%)
40/45
Model A + B + R2 50% (16%–84%)
4/8		 93% (81%–99%)
39/42		 57% (18%–90%)
4/7		 91% (78%–97%)
39/43

Abbreviations: NPV, negative predictive value; PPV, positive predictive value; pCR, pathological complete response; pPR, pathological partial response.