Fig. 11.

Low expression of TROAP inhibits melanoma growth in vivo. A Photographs of tumors obtained from the different groups of nude mice transfected with sh-NC and sh-TROAP. The average weight and tumor size were used to observe tumors. B The growth curves were determined by measuring tumor volumes every five days. C Knockdown of TROAP expression significantly inhibited melanoma cancer cell growth in nude mice and tumor weight was significantly reduced in the sh-TROAP group compared to that in the NC group. Note: *** P ≤ 0.001. ** P ≤ 0.01. * P ≤ 0.05