Fig. 7.

The landscape of melanoma sample mutation profiles. A Description of the statistical measurement mutation details, among which the most common mutation type was a missense mutation. SNP occupied an absolute proportion compared with insertion or deletion, and C > T occurred more frequently than in other classifications of forms. The horizontal histogram listed the top 10 mutated genes in melanoma. B Genetic alterations of the six LLPS-related genes in melanoma were analyzed by cBioPortal. C Comparison of tumor mutation burden (TMB) between different risk groups. D Correlation analysis between risk score and TMB. E-H TMB and association with clinical features. Low levels of TMB correlated with poorer survival with p = 0.022. High TMB levels were associated with age, gender, and pathological N classification