Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 1;23:388. doi: 10.1186/s12885-023-10847-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 9 — TROAP expression and prognostic value in melanoma. A TROAP was highly expressed in melanoma samples compared to the corresponding normal tissues of the GTEx-skin dataset as a control. The univariate B and multivariate C Cox regression analysis revealed the role of TROAP in predicting melanoma survival. D TROAP has a robust diagnostic accuracy for melanoma with an AUC value of 0.679 for the ROC curve. E TROAP copy number variation (CNV) correlates with immune cell infiltration levels in the TIMER database. F The violin represented immune cell infiltration in the low TROAP expression (blue) and the high TROAP expression (red) groups. G GSEA enrichment plots represented enriched biological pathways in high and low TROAP groups. H RT-qPCR analysis of TROAP expression of mRNA in 6 paired fresh melanoma tissues (T) and matched adjacent normal tissues (N) quantifed after transfection. I Compared with HaCaT, TROAP was up-regulated in A375 and WM-115 melanoma cell lines. J RT-qPCR was performed to measure the relative expression of TROAP in transfected with sh-RNAs or negative control (NC). Note: *** P ≤ 0.001. ** P ≤ 0.01. * P ≤ 0.05