FIG. 4.

Effects of antigen preabsorption on serum IgG reactivity (ELISA OD values) in 12 Nigerian donors show the presence of allele-specific F-seg and C-seg epitopes. Sera were absorbed with homologous and heterologous recombinant antigens prior to being tested against each of the antigens by ELISA. ■, absorption with rINT-C-seg; ○, absorption with rF-seg-INT. IgG reactivities after preabsorption with each antigen (y axes) are plotted against the reactivities without antigen preabsorption (x axes). (A) ELISA plate coated with rF-seg-INT; (B) ELISA plate coated with rINT-C-seg.