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. 2000 Oct;68(10):5575–5580. doi: 10.1128/iai.68.10.5575-5580.2000

TABLE 1.

Antibiotic susceptibilities of wild-type M. tuberculosis, the ΔsigF mutant, and the complemented mutant

Drug MIC (μg/ml)a for indicated M. tuberculosis strain
Wild type ΔsigF mutantb Complemented ΔsigF mutant
Rifampin 0.25 0.03125 0.625
Rifapentine 0.125 0.0625 NDc
Isoniazid 0.1 0.1 ND
Ethambutol 2.0 2.0 ND
Streptomycin 1.0 1.0 ND
d-Cycloserine 20 20 ND
a

MICs were determined by the Bactec method except for those for d-cycloserine, which were evaluated by agar dilution. Values are means of two to four determinations. 

b

Values for rifampin and rifapentine represent eight- and twofold increases in susceptibility, respectively, with respect to the susceptibilities of the wild type. 

c

ND, not done. 

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