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. 2023 Apr 17;10:1153537. doi: 10.3389/fmed.2023.1153537

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Copyright © 2023 Cai, Li, Long, Liao, Gong, Zheng and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of DEGs and DMGs between the uterine fibroid and normal myometrium tissue. (A) Bar plot for differentially expressed genes (DEGs) between the two groups. Red bar, down-regulated DEGs in UFs compared with NM; blue bar, up-regulated DEGs in UFs compared with NM. (B) Distribution characteristics of log2FC of differential methylation probes. The X-axis is the log2FC value of the differential methylation probe (UFs vs. NM). (C) Bar plot for differentially methylated genes (DMGs) between the two groups, Red bar, down-regulated DMGs in UFs; blue bar, up-regulated DMGs in UFs compared with NM. (D) Venn diagram of DMGs and DEGs, the overlapped part is used for further analysis. NM, normal myometrium, UFs, uterine fibroids.