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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Lancet HIV. 2020 Jun;7(6):e434–e442. doi: 10.1016/S2352-3018(20)30082-5

Table 3:

Outbreak case details

Year outbreak first observed Pre-outbreak HIV prevention services* Reduction in prevention services (eg, OST, NSP etc.)? Pre-outbreak number of HIV cases per year (PWID)* Peak outbreak HIV rate (PWID)* Previous economic problems Highly susceptible subgroups Changes in drug injection patterns Current HIV case count Percentage of cases among all cases attributable to PWID during outbreak period

Study location
 Athens, Greece 2011 Low No 10 to 20 525 cases over a one-year period (2012) Economic recession People who are homeless No ~106 cases per year (2018) 50.4%
 Bucharest, Romania 2011 Medium Yes 5 to 12 308 cases per year Poverty MSM, PWID, and CSW Increase in synthetic drug use (ie, legal highs such as bath salts) ~80 cases per year (2018) 20 to 25%
 Dublin, Ireland 2014 High No 10 to 20 57 cases over two-year period (2014 to 2015) Economic recession People who are homeless Increase in daily “snow blow” (a psychoactive drug) injections ~10 cases per year (2018) 7.4% to 10.1%
 Tel Aviv, Israel 2012 High Yes ~40 73 cases over one-year period (2012) No People who are homeless involved in sharing new synthetic cathinones without single paraphernalia and reusing paraphernalia Increase in synthetic cathinone ~25 cases per year (2016) 14.2% to 15.3%
 Luxembourg 2013 Medium No <4 68 cases over four-year period (2013 to 2017) Precarious economic situation of PWID People who are homeless Increase in cocaine supply, decrease in heroin supply 4 cases (2018) 10.7% to 22.3%
 Scott County, Indiana, USA 2014 None No <1 227 cases over three-year period (2015 to 2017) Low employment rates Multi-generational family use Prescription oxymorphone injection 10 cases (2018) >95%
 Glasgow, Scotland, UK 2015 High No ~10 48 cases over a one-year period (2015) Austerity People who are homeless, involved in criminal justice system Heroin with cocaine injection (so-called "snowballing") 26 cases (2019) 25%
 Southeastern Saskatchewan, Canada 2016 Medium No <1 16 cases over two-year period (2016 to 2017) High prevalence of poverty in Indigenous First Nations communities People who are homeless, First Nations Indigenous populations, and rural residents Unknown Hydromorphone, cocaine, and morphine were commonly reported 2 cases (2018) 73%
Summary of studies Range: 2011 to 16 1 none; 1 low; 3 medium; 3 high 2 out of 8 Range: <1 to 20 Range: 16 to 547 HIV cases (during outbreak period) 7 out of 8 People who are homeless: 6 out of 8 5 out of 8 Range: 2 to 93 cases 7.4% to >95%

CSW=commercial sex workers. MSM=men who have sex with men. NSP=needle and syringe programmes. OST=opioid substitution treatment. PWID=people who inject drugs.

*

Coverage according to UNAIDS Technical Guidelines (for OST: low, 0–20%; medium, 20–40%; high ≥40%).

PWID cases only; coverage according to UNAIDS Technical Guidelines (for NSP: low, 0–100 syringes per PWID; medium, 100–200 syringes per PWID; high, ≥200 syringes per PWID).