Table 4.
Comparison of performance in the external testing set (n = 13,988).
| Event and time point | AUC Full model (1) | AUC Perfusion abnormality (2) | AUC Clinical-only model (3) | p value (1) versus (2) | p value (1) versus (3) | p value (2) versus (3) |
|---|---|---|---|---|---|---|
| MACE at 1 year | 0.74 (0.73, 0.76) | 0.71 (0.70, 0.73) | 0.68 (0.66, 0.69) | <0.001 | <0.001 | 0.001 |
| MACE at 3 years | 0.73 (0.72, 0.74) | 0.69 (0.67, 0.70) | 0.69 (0.68, 0.71) | <0.001 | <0.001 | 0.341 |
| Death at 1 year | 0.77 (0.74, 0.80) | 0.61 (0.58, 0.65) | 0.75 (0.72, 0.78) | <0.001 | 0.320 | <0.001 |
| Death at 3 years | 0.76 (0.73, 0.78) | 0.61 (0.58, 0.64) | 0.72 (0.70, 0.74) | <0.001 | 0.026 | <0.001 |
| ACS at 1 year | 0.74 (0.70, 0.78) | 0.69 (0.64, 0.74) | 0.72 (0.68, 0.76) | 0.021 | 0.426 | 0.343 |
| ACS at 3 years | 0.72 (0.69, 0.74) | 0.65 (0.62, 0.68) | 0.70 (0.68, 0.73) | <0.001 | 0.469 | 0.012 |
| Revasc. at 1 year | 0.74 (0.73, 0.76) | 0.74 (0.72, 0.76) | 0.66 (0.64, 0.68) | 0.763 | <0.001 | <0.001 |
| Revasc. at 3 years | 0.72 (0.70, 0.74) | 0.72 (0.70, 0.74) | 0.67 (0.65, 0.69) | 0.737 | <0.001 | <0.001 |
All p values were obtained using DeLong’s test. The bold values represent statistically significant (p < 0.05) comparisons. Abbreviations: ACS acute coronary syndrome, AUC area under the receiver-operating curve, MACE major adverse cardiovascular event, Revasc. revascularization.