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. 2023 May 1;13:8. doi: 10.1038/s41387-023-00236-4

Table 5.

Association of different FAs ranges and risk of T2DM in NHANESa,b.

FAs(g/d) Q2a Pb Q3a Pb Q4a Pb
Model 1
TFA 0.808 (0.616–1.061) 0.331 0.841 (0.654–1.083) 0.402 0.609 (0.468–0.793) 0.016
TSFA 0.937 (0.746–1.177) 0.824 0.954 (0.726–1.253) 0.857 0.722 (0.561–0.928) 0.108
  4:0 0.920 (0.688–1.231) 0.824 0.968 (0.730–1.284) 0.908 0.875 (0.663–1.155) 0.613
  6:0 0.982 (0.752–1.281) 0.931 1.046 (0.803–1.362) 0.857 0.944 (0.710–1.256) 0.855
   8:0 0.981 (0.766–1.257) 0.931 1.063 (0.821–1.375) 0.826 0.897 (0.705–1.142) 0.653
  10:0 1.069 (0.834–1.371) 0.824 1.045 (0.803–1.358) 0.857 0.860 (0.665–1.114) 0.473
  12:0 1.084 (0.834–1.410) 0.824 1.053 (0.815–1.361) 0.855 0.847 (0.659–1.090) 0.416
  14:0 1.076 (0.866–1.338) 0.824 1.002 (0.781–1.285) 0.987 0.861 (0.669–1.110) 0.473
  16:0 0.987 (0.757–1.285) 0.948 0.866 (0.686–1.093) 0.459 0.739 (0.579–0.945) 0.108
  18:0 0.955 (0.746–1.223) 0.857 0.924 (0.725–1.178) 0.824 0.794 (0.619–1.017) 0.222
MUFA 0.936 (0.722–1.214) 0.826 0.770 (0.592–1.002) 0.197 0.722 (0.557–0.935) 0.108
  16:1 0.972 (0.748–1.263) 0.908 0.813 (0.613–1.078) 0.372 0.939 (0.728–1.211) 0.826
  18:1 0.994 (0.744–1.328) 0.980 0.839 (0.656–1.072) 0.382 0.711 (0.557–0.909) 0.099
  20:1 0.882 (0.656–1.184) 0.676 0.815 (0.625–1.062) 0.333 0.702 (0.521–0.947) 0.108
   22:1 0.965 (0.729–1.276) 0.905 0.842 (0.634–1.118) 0.462 1.070 (0.801–1.429) 0.826
PUFA 0.808 (0.627–1.040) 0.271 0.704 (0.514–0.964) 0.140 0.635 (0.466–0.865) 0.092
 n-6
  18:2 0.787 (0.611–1.014) 0.222 0.691 (0.514–0.929) 0.108 0.640 (0.462–0.886) 0.099
  18:3 0.817 (0.600–1.112) 0.416 0.772 (0.570–1.045) 0.271 0.642 (0.448–0.921) 0.108
  18:4 0.733 (0.540–0.996) 0.192 0.705 (0.525–0.945) 0.108 0.735 (0.556–0.971) 0.140
   20:4 1.066 (0.845–1.345) 0.824 0.817 (0.609–1.097) 0.402 1.081 (0.820–1.425) 0.824
 n-3
  20:5 0.753(0.594–0.953) 0.108 0.646 (0.489–0.854) 0.074 0.783 (0.590–1.040) 0.271
  22:5 0.976 (0.758–1.257) 0.918 0.778 (0.596–1.016) 0.222 0.748 (0.563–0.994) 0.192
  22:6 1.079 (0.842–1.382) 0.824 0.889 (0.696–1.136) 0.613 1.266 (0.980–1.635) 0.222
Model 2
TFA 0.826 (0.619–1.102) 0.709 0.929 (0.711–1.215) 0.933 0.703 (0.534–0.926) 0.012
Model 3
TFA 0.902 (0.671–1.214) 0.497 0.959 (0.720–1.277) 0.776 0.714 (0.532–0.959) 0.025

aData are aOR, 95% CIs were calculated. Q, quintile; Quintile 1 was the referent that was concealed. Model 1: unadjusted model; Model 2: adjusted for age, sex; Model 3: adjusted for age, sex, race, BMI, education, ratio of family income to poverty, smoking, exercise and hypertension.

bP value corrected by FDR.