FIGURE 2.

Mortality analysis of COVID-19 patients admitted to the general ward stratified by age decade. a) Kaplan–Meier plot of patients stratified by age decade. b) Risk of 30-day mortality with age modelled as a continuous variable. Given the nonlinear relationship between age and mortality, a restricted cubic spline function with three inner knots at default quantile locations was used. To calculate the odds ratio, the reference was set to 60 years of age. c) The same method as b), but now the 30-day mortality odds ratio is adjusted for demographics (inclusion hospital, sex and inclusion wave), age-related comorbidities (hypertension, diabetes, malignancies, immunosuppression, and chronic cardiac, neurological, respiratory and kidney disease), age-related chronic medication (antiplatelet and anticoagulant drugs), and COVID-19-related treatments both before and after sampling (corticosteroids including dexamethasone, anti-interleukin-6, imatinib, remdesivir and antibiotics).