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PLN-R14del iPSC-CMs and pathogenic features.
| iPSC-CM lines | Main pathogenic characteristics | Reference |
|---|---|---|
| Karakikes et al. | Ca2+ handling abnormalities, electrical instability | (68) |
| Cuello et al. | Ca2+ handling abnormalities, reduced force, alterations of ER/mitochondria | (67) |
| Feyen et al. | UPR activation | (72) |
| Badone et al. | Accelerated intracellular Ca2+ dynamics | (66) |
