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The F-profile VI levels in plasma cfDNA of human subjects under different oxidative stress. (A) Boxplot of F-profile VI contributions in healthy control subjects, CRC patients without and with liver metastasis. (B) Boxplot of F-profile VI contributions in patients with NPC who were subjected to chemoradiotherapy or not. Boxplots of F-profile VI contributions in the (C) fetal- and (D) maternal-specific DNA in plasma cfDNA of pregnant women across first, second and third trimesters.
