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Histological analysis of rat calvarial regeneration using DNA hydrogels. (A) Histological images of treated and untreated rat calvarial defects at 10 and 28 d after surgery. (B) Bone and connective tissue measurements among the studied groups. Significant difference is indicated by brackets (*P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001). Values were compared by a one-way ANOVA test.
