Table 2.
Relationships between serum lipid and cognitive impairment by multivariate analysis
| Variable | Total | Rural | Urban | |||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Model 1 | ||||||
| Total | ||||||
| High TC | 1.024 (0.899 to 1.167) | 0.719 | 0.934 (0.738 to 1.182) | 0.567 | 1.083 (0.924 to 1.269) | 0.324 |
| High TG | 0.836 (0.727 to 0.960) | 0.011* | 0.875 (0.674 to 1.134) | 0.313 | 0.860 (0.728 to 1.015) | 0.075 |
| High LDL-C | 1.026 (0.879 to 1.197) | 0.746 | 1.119 (0.780 to 1.607) | 0.540 | 1.050 (0.884 to 1.247) | 0.578 |
| Low HDL-C | 1.038 (0.841 to 1.282) | 0.726 | 1.130 (0.746 to 1.710) | 0.564 | 1.001 (0.782 to 1.281) | 0.994 |
| Male | ||||||
| High TC | 1.039 (0.840 to 1.285) | 0.727 | 0.948 (0.654 to 1.375) | 0.779 | 1.064 (0.819 to 1.383) | 0.640 |
| High TG | 0.679 (0.544 to 0.847) | 0.001** | 0.884 (0.592 to 1.321) | 0.548 | 0.633 (0.483 to 0.823) | 0.001** |
| High LDL-C | 0.963 (0.747 to 1.242) | 0.771 | 0.729 (0.397 to 1.339) | 0.309 | 1.059 (0.799 to 1.404) | 0.690 |
| Low HDL-C | 1.045 (0.795 to 1.374) | 0.751 | 0.984 (0.542 to 1.786) | 0.958 | 1.081 (0.794 to 1.472) | 0.622 |
| Female | ||||||
| High TC | 0.987 (0.832 to 1.171) | 0.880 | 0.912 (0.670 to 1.243) | 0.561 | 1.057 (0.859 to 1.301) | 0.598 |
| High TG | 0.954 (0.796 to 1.142) | 0.606 | 0.863 (0.613 to 1.216) | 0.401 | 1.042 (0.840 to 1.292) | 0.709 |
| High LDL-C | 1.042 (0.856 to 1.269) | 0.678 | 1.445 (0.913 to 2.289) | 0.116 | 1.020 (0.818 to 1.271) | 0.861 |
| Low HDL-C | 1.028 (0.729 to 1.449) | 0.875 | 1.315 (0.736 to 2.352) | 0.335 | 0.940 (0.613 to 1.440) | 0.776 |
| Model 2 | ||||||
| Total | ||||||
| High TC | 1.096 (0.956 to 1.256) | 0.194 | 1.013 (0.795 to 1.291) | 0.914 | 1.136 (0.961 to 1.343) | 0.136 |
| High TG | 0.940 (0.813 to 1.088) | 0.409 | 0.929 (0.711 to 1.215) | 0.591 | 0.959 (0.804 to 1.143) | 0.641 |
| High LDL-C | 1.159 (0.986 to 1.362) | 0.073 | 1.225 (0.845 to 1.776) | 0.285 | 1.127 (0.940 to 1.351) | 0.198 |
| Low HDL-C | 0.966 (0.774 to 1.204) | 0.759 | 1.081 (0.706 to 1.657) | 0.719 | 0.939 (0.724 to 1.218) | 0.635 |
| Male | ||||||
| High TC | 1.073 (0.859 to 1.340) | 0.536 | 0.986 (0.670 to 1.452) | 0.945 | 1.036 (0.784 to 1.369) | 0.803 |
| High TG | 0.785 (0.623 to 0.989) | 0.040* | 0.944 (0.622 to 1.432) | 0.785 | 0.734 (0.551 to 0.977) | 0.034* |
| High LDL-C | 1.009 (0.774 to 1.315) | 0.948 | 0.721 (0.385 to 1.351) | 0.308 | 1.074 (0.797 to 1.448) | 0.638 |
| Low HDL-C | 1.009 (0.759 to 1.341) | 0.951 | 0.957 (0.518 to 1.767) | 0.887 | 1.022 (0.737 to 1.418) | 0.638 |
| Female | ||||||
| High TC | 1.008 (0.808 to 1.257) | 0.944 | 1.057 (0.766 to 1.460) | 0.735 | 1.225 (0.982 to 1.528) | 0.072 |
| High TG | 1.067 (0.881 to 1.292) | 0.506 | 0.901 (0.629 to 1.291) | 0.571 | 1.152 (0.915 to 1.450) | 0.229 |
| High LDL-C | 1.282 (1.040 to 1.581) | 0.020* | 1.830 (1.119 to 2.991) | 0.016* | 1.165 (0.922 to 1.473) | 0.201 |
| Low HDL-C | 0.830 (0.577 to 1.194) | 0.316 | 1.231 (0.660 to 2.298) | 0.513 | 0.797 (0.504 to 1.260) | 0.331 |
*p<0.05; **p<0.01.
Model 1: crude model. Model 2: adjusted model (adjusted variables: age, education level, marital status, eating animal fat, hypertension, diabetes, physical and cognitive activities).
CI, confidence interval; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; OR, odds ratio; TC, total cholesterol; TG, triglyceride.