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. 2023 Apr 24;11(4):e006561. doi: 10.1136/jitc-2022-006561

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Post-treatment increases in tumor immune cell infiltration. (A) Intra-tumoral increases in CD8⁺ T cells in patients with matched pre-treatment (gray bar) and post-treatment (black bar) biopsies from individual patients; (B) increases in CD8⁺/Granzyme B⁺ cell density in patients with matched pre-treatment (gray bar) and post-treatment (black bar) biopsies from individual patients; (C) representative immunohistochemistry staining of one lesion (liver) with conversion from “desert” to “inflamed” phenotype (T cells shown in brown).